Back to Basics: Why the 3-Tiered Philosophy Works - PerriconeMD

Back to Basics: Why the 3-Tiered Philosophy Works

They say that good things come in threes. This idiom is particularly poignant when it comes to Dr. Perricone’s scientifically-backed approach to holistic skincare and achieving optimal health and wellness— The 3-Tiered Philosophy.


A true pioneer in the worlds of holistic wellness and skincare, Dr. Perricone is often referred to as the father of the inflammation theory of aging. The board-certified dermatologist and double-certified nutrition specialist was considered a renegade, in fact, he took the skincare world by storm in 1997 with his declaration that inflammation was enemy number one to everyone who hoped to live a long, healthy life. The launch of his line of powerful anti-inflammatory nutritional supplements and clinical skincare—quickly followed with the first of several New York Times best-sellers on his holistic approach to skincare, health, and wellness through the management of inflammation, plus an appearance on The Oprah Show—came more than five years before Time magazine famously warned America about the proven links between inflammation and a number of deadly diseases with its Feb 23, 2004 cover, the words “The Secret Killer” sprawled across its width.

As a prescription for fighting the devastating effects of aging and age-related disease caused by inflammation—the silent, systematic damage of every single organ in the body (including the brain, the heart, and the skin) over the course of years from free-radical damage—Dr. Perricone developed a comprehensive health and wellness approach that also delivers on being the ultimate holistic skincare routine. It’s called the 3-Tiered Philosophy, and it’s a whole lot more practical in everyday life (and survival) than anything Kant or Kierkegaard ever came up with.

The Perricone Approach to Optimal Health and Wellness: Inside the Holistic Wellness Routine Known as the 3-Tiered Philosophy

Unlike other trendy programs that dabble in nutrition and claim to improve the condition of the skin’s appearance, the holistic wellness focused 3-Tiered Philosophy has been proven to reduce chronic inflammation throughout the body as well as the signs of visible inflammation in the skin. It’s easy to follow, even for those who find “programs” to be a bore.

• Step 1: The Anti-Inflammatory Diet

The very basis of Dr. Perricone’s health and wellness pyramid, as well as his holistic skincare routine, this lifestyle shift revolves around the following:

  • Antioxidant-rich fresh fruits and vegetables
  • High-quality protein
  • Low-glycemic carbohydrates
  • Healthy, unsaturated fats – such as those found in nuts and olive oil
  • Foods rich in Omega-3 fatty acids – such as salmon, herring, trout, flaxseed, chia seeds, and avocados

These foods have been scientifically proven to avoid triggering an inflammatory response—and also help your cells fight off free-radical damage from factors beyond your control, like, say, environmental and climate-related damage from walking around on planet Earth. In case you needed more convincing, eating highly-nutritious anti-inflammatory foods like these also helps regulate blood pressure, blood sugar, and insulin levels and promotes healthy weight loss. It’s truly the diet that addresses every health concern, and more. (Find some of Dr. Perricone’s delicious anti-inflammatory recipe ideas here.)

Perricone MD Whole Food Supplement Collection

• Step 2: Holistic Wellness Supplements

It’s tough for even the most disciplined to always eat the right balance of foods. And those who follow an anti-inflammatory diet, day-in and day-out, will unfortunately face the reality that our bodies are not the most efficient at absorbing nutrients. That’s why Dr. Perricone created his collection of supplements that are filled with free-radical-fighting antioxidants and other essential nutrients critical to fighting the body’s inflammatory response. Some are vegan; none are coated in plastic or even partially-coated in plastic, like many other supplements; and all are formulated to be digested in the small intestines, which significantly decreases the chances of developing nausea, belching, or an aftertaste.

  Perricone MD Whole Food Supplement Collection

For those who don’t love to swallow pills, the simplest road to holistic wellness is with our Essential Multi-Vitamin Whole Foods Supplements, an especially powerful multi, and our Super Greens Supplement Powder. Super Greens takes the whole holistic wellness juicing trend to new heights, with single-serve packets, loaded with potent antioxidants and a host of other nutrients to aid in digestion and boost immunity, that taste deliciously like green apple when mixed with water.

If you’re willing to add just one more supplement to your repertoire, then that would be our Omega 3, which uses the purest source of wild sockeye salmon—which is known to have the highest and cleanest amount of Omega-3’s of all food sources on the planet. Omega-3’s, of course, are one of the biggest boosters of cardiovascular health, but they’re also excellent for maintaining cognitive skills and a healthy metabolism.

Finally, for those who want the most out of Dr. Perricone 3-Tiered Philosophy—and really enjoy the simple life—there are our Skin and Total Body Supplements packets, wrapping up everything you need beyond a multivitamin to optimize overall health and wellness as well as provide holistic skincare, joint, bone, hair, and nail benefits.

• Step 3: Clinical Skincare

The final piece of the anti-inflammatory puzzle is innovative, effective skincare. The Perricone MD line was specially formulated to infuse the skin with a high concentration of antioxidants to combat the visual signs of inflammation, feed skin the vitamins and minerals it becomes depleted of as we age, and deliver advanced anti-aging technologies to restore skin to its youthful glory. Dr. Perricone now holds over 110 patents in skin-care technology and, little-known-fact: the reason we don’t list the percentages of concentration of ingredients in our products is because, well, that percentage is irrelevant. Dr. Perricone aptly uses the analogy of baking a cake; just because the majority of the batter is flour, and there’s very little baking soda in the recipe, doesn’t mean that that tiny bit of baking soda isn’t one of the most important parts of the cake’s formulation. What’s more critical (with cakes, as with skincare) is how the ingredients are formulated to work together, in the best possible ratios.

Perricone MD Skincare

There are four key, innovative technologies that make up the foundation of Dr Perricone’s anti-inflammatory approach to skincare.

  1. Vitamin C Ester:

    One of the most important components of healthy-looking skin, the antioxidant Vitamin C Ester boosts radiance, reduces the look of dark spots and discoloration, and helps skin to look tighter and firmer. And, unlike its common counterpart, traditional Vitamin C (aka ascorbic acid, or L-ascorbic acid) it’s well-tolerated by even sensitive types. Find it en force in our Vitamin C Ester Brightening Amine Face Lift, a serum with the bonus gold-standard anti-ager,  glycolic acid.

  2. Alpha Lipoic Acid:

    This powerful free-radical fighter reduces the look of redness and blotchiness, lines and wrinkles, pore size, and lost radiance, elasticity, and firmness. Find it in the highest concentration in our High Potency Classics Face Firming Serum.

  3. DMAE:

    This nutrient is known for not only its antioxidant properties, but how extremely effective it is at boosting the look of firmness in the skin and reducing the appearance of lines and wrinkles. It’s naturally found in sardines and anchovies, and can be applied topically in abundance with our Cold Plasma Plus+ Advanced Serum Concentrate, Dr. Perricone’s so-called “multivitamin for your face,” which helps your skin adapt, day-in and day-out, so your complexion always looks its absolute youngest.

  4. Glutathione:

    Known as the body’s “master antioxidant,” Glutathione is lauded as one of the great defenders against free-radical damage and inflammation. With the highest concentration of the ingredient in all of our products, Essential Fx Acyl-Glutathione Deep Crease Serum visibly plumps deep lines, wrinkles, and creases—even those of the expression variety, including marionette lines, frown lines, smile lines, nasolabial folds, and the annoying lines at the base of our foreheads known as the “elevens.” It’s so effective at quickly knocking lines and wrinkles out of sight that it’s often referred to as “filler in a bottle.”


Your holistic skincare and wellness routine is about to get the biggest boost of its life. All you need to do is believe in the power of threes—the power, that is, of Dr. Perricone’s 3-Tiered Philosophy.